Joint toxicity assessment reveals synergistic effect of chlorpyrifos and dichlorvos to common carp (Cyprinus carpio)

Common carp (Cyprinus carpio) is an important aquaculture species. However, their production and health sometimes threatened by pesticides. In common carp, extensive studies have been done for exposures of single pesticides, but effects mixtures such as those the commonly used chlorpyrifos dichlorvos, are still unknown this first phase work, acute lethal exposure experiment was conducted to estimate 24 h 96 concentrations (LC10–90) chlorpyrifos, dichlorvos mixture. Compared found be highly toxic tested Joint toxicity assessment these pesticides in binary dominated synergism. second experimental phase, were exposed sub-lethal (LD-10% HD-50% h-LC50) individual General fish behaviors, buccal movements feeding attempts recorded after 1 h, 48 72 whereas aerobic metabolism 0–24 24–48 48–72 72–96 exposure. All pesticide treatments elevated oxygen uptake a dose dependent manner. Feeding depression also observed The augmented deleterious effect mixture suggests that joint critical develop more realistic water quality standards monitoring guidelines.